FIGURE 5 from INHBA is Enriched in HPV-negative Oropharyngeal Squamous Cell Carcinoma and Promotes Cancer Progression

Cell proliferation upon INHBA knockdown. A, Proliferation of native UDSCC1 cells, Mock KD, INHBA KD1/KD2 and native UDSCC2 cells as assessed by carboxyfluorescein succinimidyl ester (CFSE) assay and flow cytometry. Results are shown as mean ± SD of the ΔMFI (mean fluorescence intensity) normalized to UDSCC1 between t0 and t24, or t0 and t48 (n = 3). Conditions were compared with native UDSCC1 using unpaired t test with ***, P ≤ 0.001; ****, P ≤ 0.0001; and ns, P > 0.05. B, Representative flow cytometry histograms for each condition with the right peak representing t0, central peak representing t24 and left peak representing t48.