Comparison of Efficacy of Prophylactic Antibiotics in Preventing Infection with no Antibiotics Given for Removal of Impacted Mandibular Third Molar Tooth

Objective: to compare pre-operative prophylactic antibiotics with no antibiotics for removing an impacted mandibular third molar tooth to avoid Infection. Study Design: Quasi-experimental study Place and Duration of Study: Ayyub Teaching Hospital Abbottabad, Pakistan from Jan 2018 to June 2018 Methodology: Two hundred four study participants were divided into two groups: those with their third mandibular molar teeth impacted and those without. One Group was given an antibiotic before surgery; the other received a placebo. Both groups were followed after surgery and were observed for the development of post-operative Infection. Results: There were 204 participants in our study whose age group ranged from 17-30 years, (mean age 23.89±2.39 years). Of 204 individuals, 182(89.2%) were treated well, whereas 22 individuals were diagnosed with Infection (10.8%). 18 individuals (17.6%) developed Infection in the Placebo Group, whereas 4(3.9%) patients developed infection in the Antibiotic Group. Conclusion: The frequency of post-operative infections is reduced in individuals with an impacted third mandibular molar tooth who are given antibiotics before surgery.