February 24, 2024Advances in TherapyOpen Access

Psychometric Evaluation of the MENQOL Instrument in Women Experiencing Vasomotor Symptoms Associated with Menopause

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Authors

NSNeil M. SchultzAstellas Pharma (United States)AMAntonia MorgaAstellas Pharma (United Kingdom)ESEmad SiddiquiAstellas Pharma (Japan)

Discussion

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Implication

Randomized trial validates the MENQOL questionnaire in women with menopausal vasomotor symptoms, supporting its use for measuring treatment response in trials.

Key Points

The MENQOL instrument shows robust construct validity and sensitivity to change, reliably measuring health-related quality of life during menopause.
A MENQOL score reduction of ≥ 0.9 points establishes clinically meaningful improvement across 1022 participants with moderate-to-severe symptoms.
Psychometric evaluation using confirmatory factor analysis confirmed scale reliability, supporting MENQOL endpoints in fezolinetant clinical trials.

Cite This Study

Schultz et al. (2024) studied this question.

synapsesocial.com/papers/68e77b43b6db6435876efed5 https://doi.org/10.1007/s12325-024-02787-z

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Implication

Randomized trial validates the MENQOL questionnaire in women with menopausal vasomotor symptoms, supporting its use for measuring treatment response in trials.

Psychometric Evaluation of the MENQOL Instrument in Women Experiencing Vasomotor Symptoms Associated with Menopause

Discussion

Member takes

Implication

Key Points

Cite This Study

Psychometric Evaluation of the MENQOL Instrument in Women Experiencing Vasomotor Symptoms Associated with Menopause

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider