Prospects for the use of plants of the genus Kalanchoe in the creation of innovative medicines: a systematic review of chemical composition and pharmacological properties

This paper presents the results of systematization, analysis and presentation of up-to-date information on the chemical composition and biological activity of various species of the genus Kalanchoe. The study includes a review of scientific publications containing data on a wide range of active ingredients, including alkaloids, triterpenes, glycosides, flavonoids, steroids, bufadienolides, lipids, and organic acids. Examples of evidence-based studies indicating their content are given. The article discusses the importance of herbal medicines in modern society and their advantages over synthetic drugs. These medicines have a mild effect on the human body, provide a long-lasting effect, have good tolerability and minimal contraindications, and are characterized by high biological activity. Plants of the genus Kalanchoe (Kalanchoe) have a long history of use in traditional medicine due to their anti-inflammatory, wound-healing, and antimicrobial properties, but a significant portion of the species remains understudied, creating opportunities for expanding their pharmacological potential and discovering new medicinal properties. This study highlights the importance of further pharmaceutical and biological evaluation of plants in the genus Kalanchoe. This is necessary for the development of new safe and effective plant-based drugs that can contribute to progress in medicine and the pharmaceutical industry.