Cystic Hygroma in Early Pregnancy with Spontaneous Miscarriage: A Case Report

Aims: To report a rare case of first-trimester cystic hygroma and emphasize its diagnostic and prognostic implications. Case Presentation: A 42-year-old nulliparous woman with a history of miscarriage and first-degree consanguinity was admitted at 10 weeks of gestation for vaginal bleeding and lower abdominal pain. Ultrasound examination revealed a missed miscarriage associated with a multiloculated cervical/nuchal cystic hygroma. The pregnancy ended in spontaneous miscarriage within hours of admission. Genetic testing was declined. Conclusion: First-trimester cystic hygroma is a rare anomaly with a poor prognosis, frequently associated with chromosomal aneuploidy and structural malformations. Early ultrasound detection and genetic evaluation are essential for accurate diagnosis, appropriate counseling, and guiding parental decisions, particularly in resource-limited settings.