HPLC Analysis of Bioactive Constituents and in vitro Antidiabetic Potential of Ethanolic Leaf Extract of Solanum aethiopicum

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The ethanolic leaf extract of solanum aethiopicum shows moderate antidiabetic activity through α-amylase inhibition.
HPLC analysis identifies caffeic acid as the most abundant phenolic compound at 614.69 mg/L.
The extract has a total phenolic content of 83.04 mg/g and a flavonoid content of 58.11 mg/g.
Proximate analysis highlights high carbohydrate content of 83.83%, with significant levels of protein and minerals.

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This study reveals the nutritional and bioactive potential of Solanum aethiopicum, indicating its possible role in diabetes management.

Orlu et al. (2025) studied this question.

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