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February 22, 2024BiochemistryOpen Access

Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases

Dietrich Mostert Andrei Bubeneck Theresa Rauh Pavel Kielkowski Aymelt Itzen Kirsten Jung Stephan A. Sieber

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Abstract

AMPylation is a post-translational modification utilized by human and bacterial cells to modulate the activity and function of specific proteins. Major AMPylators such as human FICD and bacterial VopS have been studied extensively for their substrate and target scope

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Cite This Study

Mostert et al. (2024) studied this question.

synapsesocial.com/papers/68e781e8b6db6435876f48e9 https://doi.org/10.1021/acs.biochem.3c00568

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