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A multi-function biosensing system based on supersandwich DNA probes (SSW-DNA) and solid-state nanochannels with hydrophobic partition modification was developed by Yu Huang, Fan Xia et al. in their Research Article (e202316434). Based on the disassembly of SSW-DNA, during the target recognition, the on-site detection is achieved by introducing fluorescent molecules on SSW-DNA and using test strips. Since the entire detection system only involves one target identification process, it introduces only one potential error propagation, thereby reducing the overall risk of errors in the entire qualitative and quantitative detection process.
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Zhang et al. (2024) studied this question.
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