February 21, 2024World Journal of GastroenterologyOpen Access

Recent advances in age-related metabolic dysfunction-associated steatotic liver disease

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Authors

QHQianjun HeSun Yat-sen University YLYifei LiTongji University LZLing-Tong ZhaoBeihua University

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Implication

Review demonstrates aging-related drivers in metabolic dysfunction-associated steatotic liver disease, highlighting novel targets across aging populations.

Key Points

Aging significantly drives metabolic dysfunction-associated steatotic liver disease progression, creating an expanding global health burden across older demographics.
Review of epidemiological data indicates approximately 25% of the global population is affected, driven by impaired autophagy and disrupted mitochondrial homeostasis.
Highlights the potential for targeting oxidative stress, gut dysbiosis, and disrupted bile acid metabolism homeostasis to establish effective treatments for hepatic aging.

Cite This Study

He et al. (2024) studied this question.

synapsesocial.com/papers/68e7832ab6db6435876f5f8a https://doi.org/10.3748/wjg.v30.i7.652

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Implication

Review demonstrates aging-related drivers in metabolic dysfunction-associated steatotic liver disease, highlighting novel targets across aging populations.

Recent advances in age-related metabolic dysfunction-associated steatotic liver disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Recent advances in age-related metabolic dysfunction-associated steatotic liver disease

Discussion

Member takes

Implication

Key Points

Cite This Study

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