Mandatory Minute Ventilation (MMV) as a rescue mode of ventilation in late preterm and term infants

Mandatory Minute Ventilation (MMV) is a valuable rescue mode for late preterm and term infants experiencing challenges with hyperventilation. In this prospective study, seven infants were ventilated using MMV as a rescue mode. Infants initially under Pressure Control-Assist/Control with Volume Guarantee (PC-AC + VG) mode were transitioned to Pressure Control-MMV (PC-MMV) using Drager Babylog VN 600. All infants were late preterm or term, without major congenital malformations. Our findings suggest that transitioning to PC-MMV resulted in improved gas exchange stability, reduced respiratory rate, and facilitated early weaning. The study's strengths include prospective data collection and a uniform cohort. However, limitations include the exclusive focus on late preterm and term infants and the lack of exploration of clinical or long-term outcomes. The use of MMV as a rescue mode in these infants warrants further investigation in future clinical studies. Conclusion : MMV offers a promising approach for managing hyperventilation with increase work of breathing as a rescue mode in late preterm and term infants. Further research is needed to establish the efficacy and long-term outcomes of MMV in neonatal care.