Proteomic, miRNA and bacterial biomarker patterns in atopic dermatitis patients and their course upon anti‐IL‐4Rα therapy

Kristijan Pažur; Wojciech Francuzik; Hanin El-Mahmoud; Magdalena Kraft; Margitta Worm

doi:10.1111/jdv.19911

February 20, 2024Journal of the European Academy of Dermatology and VenereologyOpen Access

Proteomic, miRNA and bacterial biomarker patterns in atopic dermatitis patients and their course upon anti‐IL‐4Rα therapy

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Key Points

Tracking proteomic, miRNA, and bacterial biomarkers in atopic dermatitis indicates that molecular profiles may predict targeted therapy effectiveness.
Evaluation focuses on longitudinal changes in bacterial biomarkers and miRNA profiles during anti-IL-4Ra therapy within a systems medicine framework.
Characterizing multi-omic biomarker shifts may enable accurate diagnosis in atopic dermatitis and optimize patient selection for targeted treatment.

Implication

Biomarker analysis explores molecular profiles in atopic dermatitis, suggesting potential for personalizing targeted therapy.

Abstract

Identification of biomarkers is required for a systems medicine approach and personalized treatment in atopic dermatitis (AD). These biomarkers may not only aid in diagnosing but also might be suitable to predict the effectiveness of targeted treatment.

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Cite This Study

Pažur et al. (2024) studied this question.

synapsesocial.com/papers/68e786e5b6db6435876f9103 https://doi.org/10.1111/jdv.19911

View Full Paper

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Proteomic, miRNA and bacterial biomarker patterns in atopic dermatitis patients and their course upon anti‐IL‐4Rα therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

Proteomic, miRNA and bacterial biomarker patterns in atopic dermatitis patients and their course upon anti‐IL‐4Rα therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

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