Metagenomic next-generation sequencing for diagnosis of fatal Balamuthia amoebic encephalitis

This is the authors' abstract. We don't add key points for this paper.

Balamuthia amoebic encephalitis (BAE), caused by Balamuthia mandrillaris, is a rare and life-threatening infectious disease with no specific and effective treatments available. The diagnosis of BAE at an early stage is difficult because of the non-specific clinical manifestations and neuroimaging.