Advancing Translational Research: Humanized Rodent Models Integrating Full-Thickness Human Skin and Autologous Immune Cells

This research article investigates the frontier of translational research, unveiling an innovative paradigm in the form of humanized mouse and rat models. Integrating full-thickness human skin and autologous immune cells, this approach holds tremendous potential to elevate the translational relevance of preclinical studies, providing a more faithful representation of human biology. We delve into the methodology, applications, challenges, and future directions of these advanced models, elucidating their transformative impact on biomedical research.