Green Synthesis of TiO₂ Nanoparticle in Morus nigra Leaves; Characterization and Biological Potential

Titanium dioxide nanoparticles (TiO 2(Aq) and TiO 2(Et) ) were synthesized by treating titanium tetraisopropoxide (TTIP) with the aqueous/ethanolic extracts of Morus nigra leaves.The synthetic method is an environmentally friendly, inexpensive and beneficial as the plant leaves act as stabilizing and reducing agents.The obtained NPs were characterized by FTIR spectroscopy, X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM) and Raman spectroscopy.The crystallite sizes of TiO 2(Aq) and TiO 2(Et) NPs were found to be 0.17 and 0.076 nm, respectively.FTIR spectroscopy have shown the coating of plant material upon the surface of nanoparticles.SEM analysis has shown the round shape and irregular surface morphologies of nanoparticles.The bio-synthesized TiO 2 NPs displayed negligible toxic hemolytic effects and had a little inhibition of Staphylococcus aureus and Proteus Mirabilis bacteria as compared to ciprofloxacin.