February 12, 2024Open Access

The Relationship of Cerebrospinal Fluid Biomarkers and Cognitive Performance in Frontotemporal Dementia

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Elevated cerebrospinal fluid total tau levels correlate with reduced cognitive scores across frontotemporal dementia and Alzheimer disease cohorts.
With correlation r=-0.469, total tau links negatively to Montreal Cognitive Assessment scores in frontotemporal dementia, while phosphorylated tau shows no link.
Retrospective cohort analysis of 61 patient records highlights cerebrospinal fluid total tau as a key marker of cognitive impairment in frontotemporal dementia.

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Implication

Retrospective cohort study reveals inverse correlation between cerebrospinal fluid total tau and cognitive performance in frontotemporal dementia, highlighting distinct tau pathology.

Cite This Study

Çayır et al. (2024) studied this question.

synapsesocial.com/papers/68e79960b6db6435877093bd https://doi.org/10.21203/rs.3.rs-3945509/v1

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Implication

Retrospective cohort study reveals inverse correlation between cerebrospinal fluid total tau and cognitive performance in frontotemporal dementia, highlighting distinct tau pathology.

The Relationship of Cerebrospinal Fluid Biomarkers and Cognitive Performance in Frontotemporal Dementia

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Cite This Study

The Relationship of Cerebrospinal Fluid Biomarkers and Cognitive Performance in Frontotemporal Dementia

Key Points

Discussion

Implication

Cite This Study

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