Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 11, 2024Scientific ReportsOpen Access

Structure–activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling

View Full Paper
Ask AI
Bookmark
Share

Authors

AAAhmed A. AhmedLatakia UniversitySCShuang ChenShihezi UniversityMRMaria Roman-EscorzaKing's College London

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Ahmed et al. (2024) studied this question.

synapsesocial.com/papers/68e7997bb6db64358770a02fhttps://doi.org/10.1038/s41598-024-54080-2
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1HELIX FORMATION BY GUANYLIC ACID1962 · 1,666 citations
  2. 2Discovery of novel small molecule inhibitors of S100P with in vitro anti-metastatic effects on pancreatic cancer cells2020 · 30 citations
  3. 3A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer2015 · 117 citations
  4. 4Disentangling the Structure–Activity Relationships of Naphthalene Diimides as Anticancer G-Quadruplex-Targeting Drugs2021 · 56 citations
  5. 5A G-quadruplex-binding compound shows potent activity in human gemcitabine-resistant pancreatic cancer cells2020 · 32 citations