Green Synthesis of Silver Nanoparticles using Endostemon viscosus (Roth) aqueous leaf extract; Characterization; Evaluation of Antibacterial, DPPH and Anticancer efficacy

Nanoparticles are being constantly exploited through scientific community because of their multifaceted properties and applications. Production of biogenic silver nanoparticles (AgNPs) with plant material is extremely cost effective and environmentally non-hazardous. Plant extracts are wealth of various phytochemicals such as secondary metabolites and frequently act as reducing and capping agents in the synthesis of nanoparticles. The present study deals with the synthesis of silver nanoparticles by the aqueous leaf extract of Endostemon viscosus (Roth). Synthesized silver nanoparticles characterized by different recent spectroscopic tools such as UV-Visible spectrophotometer, DLS-Zeta potential, FT-IR, TEM with EDS, and XRD (X-ray diffraction). UV-Vis showed that the peak at 414 nm. DLS-Zeta potential analysis revealed about stability and even size of the particles. FT-IR was studied to know what phyto-constituents are actually acting as capping and stabilization of the nanoparticles. TEM is used to find shape, size and agglomeration pattern of the nanoparticles. TEM image exhibited size range from 11.03 to 37.87 nm and average size of the EvL-AgNPs are 16.77 nm. Eventually green synthesized nanoparticles are evaluated for their efficacy on anti-bacterial, DPPH, and anti-cancer activities. Biologically synthesized EvL-AgNPs expressed excellent anti-bacterial, anti-oxidants, and anti-cancer activities. Hence, the bio-synthesized AgNPs could be considered as auspicious therapeutic option against infectious pathological situations.