Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 9, 2025European Journal Of HaematologyOpen Access

Herpes Zoster in Hematological Disorders: Pathogenesis, Risk Stratification, and Emerging Strategies for Prevention and Immunization

View Full Paper
Ask AI
Bookmark
Share

Authors

EMEnrica Antonia MartinoEVErnesto VignaABAntonella Bruzzese

Discussion

Loading...

Member takes

Overview

This review highlights the risk of herpes zoster in immunocompromised patients, suggesting tailored vaccination and antiviral options.

Key Points

  • In immunocompromised patients, herpes zoster incidence may exceed 30–60 per 1000 person-years.
  • The adjuvanted recombinant zoster vaccine shows 68%–87% efficacy in heavily immunosuppressed individuals.
  • Emerging mRNA-based vaccines may improve immunogenicity for those at risk of herpes zoster.
  • Antiviral prophylaxis is essential for preventing herpes zoster in patients with hematological disorders.

Cite This Study

Martino et al. (2025) studied this question.

synapsesocial.com/papers/68e7ba40ccde5f1021f64aa0https://doi.org/10.1111/ejh.70049
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK2024 · 23 citations
  2. 2Impact of Herpes Zoster and Post-Herpetic Neuralgia on Health-Related Quality of Life in Japanese Adults Aged 60 Years or Older: Results from a Prospective, Observational Cohort Study2017 · 65 citations
  3. 3Herpes Zoster2002 · 782 citations
  4. 4Infectious complications of CD19-targeted chimeric antigen receptor–modified T-cell immunotherapy2017 · 585 citations
  5. 5Varicella zoster virus mRNA vaccine candidate induced superior cellular immunity and comparable humoral and Fc-mediated immunity compared to the licensed subunit vaccine in a mouse model2025 · 5 citations