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October 9, 2025Frontiers in MedicineOpen Access

Clinical observations of high-flow nasal cannula oxygenation in endobronchial ultrasound-guided transbronchial needle aspiration: a randomized controlled study

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This randomized controlled study shows reduced hypoxia rates with high-flow nasal cannula oxygenation compared to nasopharyngeal tube oxygenation.

The incidence of hypoxia was only 4.9% in the HFNC group versus 25.0% in the NPT group.
Jaw lifting and mask-assisted ventilation for hypoxia occurred significantly less in the HFNC group.
At various time points, the HFNC group maintained higher PaO2 and lower PaCO2 levels.
No significant differences in heart rate, blood pressure, or adverse events were observed between the groups.

Yue et al. (2025) studied this question.

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This randomized controlled study shows reduced hypoxia rates with high-flow nasal cannula oxygenation compared to nasopharyngeal tube oxygenation.