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October 9, 2025Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )Open Access

Preliminary Evaluation of Tacrolimus Impact on Glycemic Control, Renal Function, and Hematological Inflammatory Markers in Kidney Transplant Recipients

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Authors

SRShvan Burhan RafiqTATavga Ahmed AzizBNBryar Ezadeen Nuradeen

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Overview

Pilot study reveals tacrolimus improves glycemic control and renal function in kidney transplant recipients, indicating its metabolic benefits.

Key Points

  • Tacrolimus administration significantly reduces fasting blood glucose and serum creatinine in kidney transplant recipients.
  • After three months, fasting blood glucose and serum creatinine improved in females, and tacrolimus trough levels declined in both sexes.
  • No significant changes in hematological indices such as NLR, MLR, or PLR were observed in relation to tacrolimus concentration groups.
  • Future research should address larger cohorts to confirm sex-related differences in tacrolimus pharmacokinetics and effects.

Cite This Study

Rafiq et al. (2025) studied this question.

synapsesocial.com/papers/68e7ba40ccde5f1021f64bd1https://doi.org/10.54133/ajms.v9i2.2392
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of Therapeutic Monitoring of Tacrolimus with Laboratory Markers of Kidney Function in Receptors of Kidney Allograft2024
  2. 2Plasma versus Whole Blood Tacrolimus Concentration and Outcomes After Kidney Transplantation2026
  3. 3Studying the Blood Trough Level of Tacrolimus on Patients after Kidney Transplant at the Uronephreulogical Department, Bach Mai Hospital, Vietnam2024
  4. 44CPS-214 Monitoring of tacrolimus in a kidney transplanted cohort2024
  5. 5Optimum tacrolimus trough levels for enhanced graft survival and safety in kidney transplantation: a retrospective multicenter real-world evidence study2024 · 11 citations