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October 9, 2025Advanced ScienceOpen Access

Cancer: From a Genetic Disorder to a Systemic Disease

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Authors

AWAda Hang‐Heng WongAgency for Science, Technology and ResearchYHYuming Hu303 Hospital of People's Liberation Army

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Implication

Analysis reveals cancer's evolution from a genetic disorder to a systemic disease, suggesting new translational research avenues and therapeutic interventions.

Key Points

  • Cancer treatment outcomes improved through systemic approaches in understanding molecular mechanisms and environmental interactions, highlighting genetic disorder aspects.
  • Significant insights were gathered on the tumor microenvironment and the roles of proto-oncogenes and tumor suppressor genes in cancer evolution.
  • Observational analysis targeting the relationship between epigenetics and carcinogenesis will drive innovative therapeutic interventions in clinical applications.
  • Advances in digital twins technology and artificial intelligence aim to enhance patient stratification for personalized cancer therapy based on multi-omic data.

Cite This Study

Wong et al. (2025) studied this question.

synapsesocial.com/papers/68e7d631bd66d359be62660bhttps://doi.org/10.1002/advs.202518885
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