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October 9, 2025PeerJOpen Access

Optimal treatment options for acne scars in patients with historic acne: a systematic review and network meta-analysis

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Authors

BWBingwei WuQilu University of TechnologyMGMingju GaoWenshan UniversityYZYixuan ZhangGuangxi University

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Implication

Systematic review demonstrates the efficacy of laser therapies in reducing acne scars in patients, suggesting treatment optimization.

Key Points

  • Laser combined with PRP ranked best in reducing acne scars, highlighting effective treatment options.
  • Results from 68 randomized controlled trials indicate laser + chemical peels yield the highest patient satisfaction.
  • Microneedling was observed as the most tolerable treatment option regarding pain levels during procedures.
  • No strong evidence was found suggesting any treatment significantly reduced erythema or post-inflammatory hyperpigmentation.

Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/68e7d631bd66d359be6268e4https://doi.org/10.7717/peerj.19938
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