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October 9, 2025Open Access

Synthesis, Characterization and Antibacterial properties of Cr(II), Co(II), Ni(II) and Cu(II) Schiff Base Complexes Derived from 1,3-diphenylpropane-1,3-dione and Glycine

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Authors

SYSulaiman Sani YusufUmaru Musa Yar'adua UniversityISIbrahim SamailaUmaru Musa Yar'adua UniversityMYMuslim YusufUmaru Musa Yar'adua University

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Implication

Synthesis of metal complexes shows enhanced antibacterial effects against E. coli and S. pneumoniae, suggesting potential for new antibacterial agents.

Key Points

  • Antibacterial screening revealed significantly higher activity for metal complexes than the free ligand.
  • The [Ni(L)]Cl₂ and [Co(L)]Cl₂ complexes displayed inhibition zones of 20 mm and 19 mm against E. coli.
  • Chelation in metal complexes enhances their lipophilicity, improving penetration into microbial membranes.
  • Metal complexes exhibit different structural and biological properties based on the metal identity.

Cite This Study

Yusuf et al. (2025) studied this question.

synapsesocial.com/papers/68e80eb363e2e2f707877ae4https://doi.org/10.33003/chemclass-2025-0903/13
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Also Consider

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