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This is a Literature Review study.

The role of gut microbiota in the pathogenesis of Parkinson’s disease: mechanisms of influence and therapeutic perspectives (review)

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This review highlights how gut microbiota imbalance influences Parkinson's disease progress, suggesting new therapeutic strategies.

Gut microbiota imbalance may trigger Parkinson's disease, leading to neuroinflammation and the loss of dopaminergic neurons.
Research indicates that intestinal dysbiosis affects both immune responses and the central nervous system through gut-brain axis mechanisms.
Therapeutic strategies being explored include probiotics, prebiotics, and fecal microbiota transplantation targeting gut health.
Despite promising findings, the effectiveness of these interventions remains unproven, necessitating larger randomized controlled trials.

A.O. VASYLEVYCH (2025) studied this question.

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