A rare renal cell carcinoma treated successfully, with no recurrence observed nine months after nephrectomy, suggesting positive outcomes for such cases.
Bellini duct carcinoma is a very rare and aggressive histological type of renal cell carcinoma. It accounts for less than 1% of renal cancers. It originates in the epithelial layer of the Bellini duct, which is the distal part of the nephron, with a median survival time of less than one year in the metastatic stage. We report the case of a 69-year-old patient admitted for a painless swelling of the right flank, which had developed gradually. Computed tomography revealed a large mass in the right middle kidney. The patient underwent an extended right nephrectomy. Histopathological examination coupled with immunohistochemical analysis revealed carcinoma of the renal collecting ducts. Positron emission tomography (FDG PET scan) did not reveal any hypermetabolic foci associated with lymph node or metastatic involvement. The patient did not receive adjuvant chemotherapy and was placed under surveillance. The outcome is exceptionally favourable 9 months after surgery: no recurrence, locoregional metastases or distant metastases.
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Aroni et al. (2025) studied this question.
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