Synthesis of naphthoquinone-based probes improves activity-based protein profiling of oxidoreductases, suggesting new insights into enzyme functions.
Activity-based protein profiling (ABPP) has become a highly valuable proteomic technique over the past decades especially in the investigation of hydrolytic enzymes. Oxidoreductases have so far received less attention as...
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Krammer et al. (2025) studied this question.
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