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October 10, 2025MedicinaOpen Access

Ticagrelor Versus Clopidogrel in Patients with Acute Coronary Syndrome and Chronic Kidney Disease: A Real-World Analysis from a National Registry

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Authors

TWTzu-Lin WangVWVictor Chien‐Chia WuKSKou‐Gi Shyu

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Overview

Retrospective cohort study demonstrates ticagrelor increases cardiovascular events in patients with ACS and CKD, suggesting caution in this population.

Key Points

  • Ticagrelor is associated with higher risks of myocardial infarction compared to clopidogrel in CKD patients.
  • Patients treated with ticagrelor showed significant higher rates of cardiovascular-related readmission than those on clopidogrel.
  • This retrospective cohort study used the TSOC ACS-DM registry to analyze data on diabetes and CKD patients.
  • Findings indicate that antiplatelet choice may significantly impact cardiovascular outcomes in high-risk populations.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68e861857ef2f04ca37e3ba4https://doi.org/10.3390/medicina61101804
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