This case study highlights the limitations of ultrasonography and CT for assessing bilateral non-palpable cryptorchidism, emphasizing the need for MRI and endocrine markers.
Bilateral non-palpable cryptorchidism is a rare yet clinically significant entity associated with infertility, malignancy, and disorders of sexual development. We report the case of a 5-year-old boy with bilaterally empty scrotal sacs in whom both ultrasonography and contrast-enhanced CT failed to identify testicular tissue. This case illustrates the limitations of conventional morphological imaging and underscores the crucial role of MRI, endocrine assessment—including anti-Müllerian hormone (AMH), inhibin B/FSH ratios, and emerging markers such as INSL3—and diagnostic laparoscopy. A multidisciplinary strategy involving radiology, endocrinology, and pediatric urology remains indispensable for accurate diagnosis and timely management.
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Hassan et al. (2025) studied this question.
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