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October 10, 2025Jurnal Farmasi Sains dan PraktisOpen Access

ANALYSIS OF ADVERSE DRUG REACTIONS (ADRs) AND THEIR SEVERITY IN BREAST CANCER PATIENTS TREATED WITH THE DOCETAXEL-DOXORUBICIN REGIMEN AT SULTAN AGUNG ISLAMIC HOSPITAL

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Authors

MSMuh Maskur SetiajiZCZakky Cholisoh

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Overview

Quantitative analysis reveals incidence of adverse drug reactions in breast cancer patients, indicating critical safety concerns.

Key Points

  • Breast cancer patients treated with the docetaxel-doxorubicin regimen experienced various adverse drug reactions, with nausea as the most frequent.
  • Out of 591 recorded adverse drug reactions incidents, 55.6% were identified as mild, while anemia and alopecia were notable in moderate and severe categories respectively.
  • The study employed a quantitative cross-sectional approach, utilizing purposive sampling to gather data on adverse drug reactions.
  • These findings may highlight the need for monitoring and managing adverse drug reactions in patients undergoing chemotherapy.

Cite This Study

Setiaji et al. (2025) studied this question.

synapsesocial.com/papers/68e861a57ef2f04ca37e4726https://doi.org/10.31603/pharmacy.v11i2.12956
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Scientific Analysis with a Retrospective Method on the Incidence and Severity of Adverse Drug Reactions in Hospitalized Cancer Patients2024
  2. 2Prospective Randomized Trial of Docetaxel Versus Doxorubicin in Patients With Metastatic Breast Cancer1999 · 641 citations
  3. 3Assessing the real-world safety of docetaxel for non-small cell lung cancer: Insights from a comprehensive analysis of FAERS data.2025
  4. 4ADVERSE DRUG REACTION OF ANTICANCER DRUGS AMONG BREAST CARCINOMA PATIENTS OF TERTIARY CARE UNIVERSITY HOSPITAL OF CENTRAL INDIA2024
  5. 5A Prospective Observational Study on the Prescription Pattern of Anticancer Drugs and Adverse Reactions of Chemotherapy in Patients with Breast Cancer2024