Chemically Inducible Antisense Oligonucleotides for Cell-Specific Gene Silencing

Q: What type of study is this?

This is a Quantitative Study study.

Zhen Xun; Yang Hai; Lijuan Tang; Jian-Hui Jiang; Zhenkun Wu

doi:10.1039/d5cb00186b

January 1, 2025RSC Chemical BiologyOpen Access

Chemically Inducible Antisense Oligonucleotides for Cell-Specific Gene Silencing

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Key Points

Targeted gene silencing is achieved through chemically inducible antisense oligonucleotides, enhancing precision.
The approach minimizes adverse effects in normal cells, which is crucial for effective gene therapy.
Cell-specific control allows for improved therapeutic outcomes in gene-targeting strategies.
This research presents a significant step towards safer and more efficient gene therapy applications.

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Implication

Research shows enhanced gene silencing in targeted cells using antisense oligonucleotides, highlighting potential for safer gene therapy.

Abstract

The ability of cell-specific control of the function of antisense oligonucleotides (ASO) is highly desirable for precise gene therapy with minimizing adverse effect in normal cells. Here we report a...

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Cite This Study

Xun et al. (2025) studied this question.

synapsesocial.com/papers/68e865117ef2f04ca37e4e93 https://doi.org/10.1039/d5cb00186b

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Chemically Inducible Antisense Oligonucleotides for Cell-Specific Gene Silencing

Key Points

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Implication

Abstract

Discussion

Cite This Study

Chemically Inducible Antisense Oligonucleotides for Cell-Specific Gene Silencing

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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