Observational analysis demonstrated enhanced solubility and bioavailability of Bundung extract using self-nanoemulsifying drug delivery systems.
Key Points
Formulation 1 of L-SNEDDS achieved 99.3% transmittance and had the smallest droplet size, indicating excellent emulsification.
Formulation 1 also showed the highest antioxidant activity, making it a promising option for oral delivery of Bundung extract.
Using a spray drying technique, formulation 3 converted liquid SNEDDS to solid SNEDDS with a 100% yield, optimizing drug delivery.
Characterization tests including droplet size, polydispersity index, and zeta potential confirmed that formulations 1, 2, 3, and 5 met the required standards.