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November 11, 2025Micro and Nanosystems

Rutin-Self-nanoemulsifying Drug Delivery System: Development, Characterization, Pharmacokinetics, and Anti-ulcer Evaluation

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Authors

RPRashmi PathakPCPHOOL CHANDRA

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Overview

Rutin-SNEDDS improves bioavailability and pharmacokinetics in anti-ulcer treatment, suggesting strong gastroprotective potential.

Key Points

  • Rutin-SNEDDS significantly enhances bioavailability and pharmacokinetic parameters of rutin, supporting its therapeutic effectiveness.
  • Acute oral toxicity studies demonstrate that rutin-SNEDDS has no observed toxicity, ensuring safety for potential applications.
  • Formulated using propylene glycol and olive oil, rutin-SNEDDS shows effective droplet size and emulsification time, ensuring improved delivery.
  • Enhanced anti-ulcer and antioxidant activities highlight rutin-SNEDDS potential as a gastroprotective agent in vivo.

Cite This Study

Pathak et al. (2025) studied this question.

synapsesocial.com/papers/69252ea8c0ce034ddc356a0bhttps://doi.org/10.2174/0118764029385825251008005124
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