Pilot study reports on reduced well-being in vitiligo patients, indicating WHO-5 tool's utility for screening.
Summary Background Only a few studies exist on the psychosocial impact of vitiligo in German patients, in particular those affected in genital and visible body areas. Methods This monocentric pilot study aimed to assess well‐being of adult patients with vitiligo and to compare sex, age, and clinical characteristics between patients with and without genital, facial and hand involvement. Well‐being was assessed using the WHO‐5 questionnaire and quality of life with the Dermatology Life Quality Index (DLQI). Furthermore, psychometric properties of the WHO‐5 well‐being index were tested. Results In total, 110 patients (mean age ± SD: 47.5 ± 14.7 years; 54.5% female; 95.5% with non‐segmental vitiligo) were included. The WHO‐5 mean score was 13.3, with 46 patients (42.2%) having a score < 13, indicating reduced well‐being. Sixteen patients (14.7%) had a WHO‐5 score < 7, indicating a high probability of depression. No significant differences in WHO‐5 or DLQI scores were found between patients with vs without genital, facial, and hand involvement. Psychometric properties were confirmed to be good. Conclusions Our findings emphasize the psychosocial impact of vitiligo in German patients, as reflected by reduced well‐being, and suggest the usefulness of the WHO‐5 as a simple psychosocial screening tool for routine care.
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Ohlenbusch et al. (2025) studied this question.
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