Numerical analysis reveals the electrostatic effect enhances particle dispersion in bifurcated tubes, indicating advancements for inhalation therapy.
As the prevalence of respiratory diseases continues to rise, inhalation therapy has emerged as a crucial method for their treatment. The effective transmission of medications within the respiratory tract is vital to achieve therapeutic outcomes. Given that most inhaled particles carry electrostatic charges, understanding the electrostatic effect on particle behavior in bifurcated tubes is of significant importance. This work combined Large Eddy Simulation-Lagrangian particle tracking (LES-LPT) technology to simulate particle behavior with three particle sizes (10, 20, and 50 μm) from G2 to G3 (“G” stands for generation) in bifurcated tubes, either with or without electrostatics, under typical human physiological conditions (Re = 1036). The results indicate that the electrostatic force has a significant effect on particle behavior in bifurcated tubes, which increases with particle size. Within the bifurcated tubes, the electrostatic force enhances particle movement in alignment with the secondary flow as well as intensifies the interaction of particles with local turbulent vortices and promotes particle dispersion rather than agglomeration. On the other hand, the distribution of the electrostatic field is influenced by particle behavior. Higher particle concentration presents stronger electrostatic strength, which increases with particle size. Therefore, it can be concluded that the electrostatic interactions among particles can prevent particles from aggregating and enhance the efficiency of inhalation therapy.
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Zhao et al. (2025) studied this question.
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