Observational analysis found that re-entrant microstructures affect cancer cell adhesion and morphology, suggesting new design strategies for biointerfaces.
Cancer Cells on Re-Entrant Microstructures The Research Article DOI:10.1002/admi.202500631 by Nam-Trung Nguyen, Navid Kashaninejad, and co-workers explores how re-entrant microstructured surfaces with varied cap geometries and materials influence cancer cell adhesion, morphology, and proliferation. By integrating curvature, confinement, and wettability cues, the study reveals geometry-dependent mechanosensitive responses, advancing the understanding of cell-material interactions and offering design strategies for stable, long-term biointerfaces.
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Vu et al. (2025) studied this question.
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