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This is a Literature Review study (also classified as: Quantitative Study).

October 12, 2025Open Access

Gut Microbiota under Microgravity: Current Advances, Challenges, and Future Directions

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Review reveals alterations in gut microbiota composition during microgravity, highlighting potential health risks and intervention strategies.

Microgravity significantly alters gut microbiota composition, increasing risks for astronaut health during long missions.
Shifts in microbial diversity and community structure under microgravity can lead to metabolic disorders and immune dysfunction.
Targeted interventions like probiotics and dietary changes could mitigate dysbiosis in space conditions.
Future research must integrate advanced biotechnology to improve astronaut safety and understanding of gut dynamics.

Sun et al. (2025) studied this question.

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Review reveals alterations in gut microbiota composition during microgravity, highlighting potential health risks and intervention strategies.