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October 12, 2025EpidemiologiaOpen Access

Basal Ganglia Involvement in Pediatric Mycoplasma pneumoniae Meningoencephalitis: Two Cases and a Literature Review

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Authors

DLDominik LjubasLŠLuka ŠvitekLMLorna Stemberger Marić

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Overview

Case reports demonstrate basal ganglia involvement in mycoplasma pneumoniae meningoencephalitis, highlighting diagnostic challenges.

Key Points

  • Both pediatric patients exhibited bilateral basal ganglia lesions, which completely regressed during follow-up.
  • M. pneumoniae was confirmed in both cases through serological assays and PCR, emphasizing diagnostic approaches.
  • Literature review identified 21 cases with similar basal ganglia involvement, showcasing the rarity of this complication.
  • Diagnosis may be aided by recognizing basal ganglia lesions, especially when respiratory symptoms are mild or absent.

Cite This Study

Ljubas et al. (2025) studied this question.

synapsesocial.com/papers/68ebe3d6becc64ad52fdac95https://doi.org/10.3390/epidemiologia6040062
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Necrotizing Encephalopathy and Cerebral Infarction Triggered by Mycoplasma pneumoniae Infection in a Pediatric Patient: A Rare Clinical Association2025
  2. 2Movement Disorders and Cerebellar Syndromes Associated with <i>Mycoplasma pneumoniae</i> Infection: A Systematic Review2026
  3. 3Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection2016 · 27 citations
  4. 4<i>Mycoplasma pneumoniae</i> -associated central nervous system manifestations: current knowledge and challenges2026
  5. 5Clinical features and short-term outcomes in children with Mycoplasma pneumoniae encephalitis2026