What type of study is this?

This is a Case-Control Study study.

October 12, 2025Cancer ReportsOpen Access

Potential of Serum ApoC1 as a Noninvasive Biomarker for Breast Cancer Detection and Prognosis: A Prospective Case–Control Study

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Authors

AKAbolfazl Khalafi‐NezhadShiraz University of Medical Sciences MBMahdi BarazeshGerash University of Medical Sciences AAAhmad AbdollahiGerash University of Medical Sciences

Discussion

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Implication

This case–control study finds ApoC1 levels accurately identify breast cancer, suggesting its potential as a reliable diagnostic and prognostic biomarker.

Key Points

ApoC1 concentrations were significantly lower in breast cancer patients compared to healthy controls.
The study achieved 100% sensitivity, specificity, and accuracy for diagnosing breast cancer using ApoC1 levels.
ROC curve analysis confirmed ApoC1 as a promising biomarker with optimal cutoff values indicating excellent diagnostic performance.
HER2 over-expression in breast cancer patients showed a significant difference in ApoC1 levels, enhancing its prognostic value.

Cite This Study

Khalafi‐Nezhad et al. (2025) studied this question.

synapsesocial.com/papers/68ebe3d6becc64ad52fdad9d https://doi.org/10.1002/cnr2.70359

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October 12, 2025Cancer ReportsOpen Access

Potential of Serum ApoC1 as a Noninvasive Biomarker for Breast Cancer Detection and Prognosis: A Prospective Case–Control Study

View Full Paper

Ask AI

Bookmark

Authors

AKAbolfazl Khalafi‐NezhadShiraz University of Medical Sciences MBMahdi BarazeshGerash University of Medical Sciences AAAhmad AbdollahiGerash University of Medical Sciences

Discussion

Member takes

Implication

This case–control study finds ApoC1 levels accurately identify breast cancer, suggesting its potential as a reliable diagnostic and prognostic biomarker.

Key Points

ApoC1 concentrations were significantly lower in breast cancer patients compared to healthy controls.
The study achieved 100% sensitivity, specificity, and accuracy for diagnosing breast cancer using ApoC1 levels.
ROC curve analysis confirmed ApoC1 as a promising biomarker with optimal cutoff values indicating excellent diagnostic performance.
HER2 over-expression in breast cancer patients showed a significant difference in ApoC1 levels, enhancing its prognostic value.

Cite This Study

Khalafi‐Nezhad et al. (2025) studied this question.

synapsesocial.com/papers/68ebe3d6becc64ad52fdad9d https://doi.org/10.1002/cnr2.70359

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