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October 12, 2025Open Access

Interfacing Quantum Computing Systems with High-Performance Computing Systems: An Overview

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This overview showcases the integration of quantum computing and high-performance computing systems, highlighting key challenges and methodologies.

Hybrid HPC-QC systems enhance capabilities in solving complex problems and optimizing processes.
Existing integration models range from loosely coupled to tightly integrated architectures, each with distinct challenges.
Prominent frameworks including Qiskit and CUDA-Q facilitate software stack development for hybrid environments.
Challenges like coherence and scalability highlight ongoing research needs for better integration and efficiency.

Rallis et al. (2025) studied this question.

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This overview showcases the integration of quantum computing and high-performance computing systems, highlighting key challenges and methodologies.