Observational analysis identifies future strategies for advancing vaccines and therapies in infectious diseases, highlighting the importance of equitable clinical trials.
The Infectious Diseases Clinical Research Consortium and Vaccine Treatment Evaluation Units (VTEUs) are a network of clinicians and scientists who work together with the National Institutes of Allergy and Infectious Diseases to advance vaccines and therapeutics to combat infectious diseases. For more than 60 years, the VTEUs have led Phase 1–4 clinical trials, with a strong focus on Phase 1/2 trials, evaluating the safety, reactogenicity, optimal doses, routes of administration, and schedules for vaccines and treatments. Our future goals focus on advancing vaccine science and innovation through clinical and translational studies; achieving equitable representation in clinical trials across the human lifespan to facilitate disease prevention in vulnerable populations; advancing national and global health priorities through collaborations that leverage complementary strengths and foster preparedness and rapid responses; and developing the next generation of clinical and translational researchers through structured mentorship and training opportunities. Our long-term vision is to develop safe and effective vaccines and therapeutics to combat infectious diseases and enhance health and well-being for all.
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Whitaker et al. (2025) studied this question.
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