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October 12, 2025Journal of Applied Pharmaceutical ScienceOpen Access

Hypoglycemic potential of Sargassum spp.: A review of bioactive compounds for diabetes management

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Authors

MFMuhamad FirdausAPAhmad Faris Priambodo

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Overview

This review evaluates hypoglycemic effects of Sargassum bioactive compounds, suggesting new diabetes treatments.

Key Points

  • Extracts from eleven Sargassum species significantly lowered fasting glucose in rodent models, suggesting their potential in diabetes management.
  • Key constituents like polyphenols and terpenoids improved insulin sensitivity and lipid profiles, indicating robust therapeutic effects.
  • This review evaluated 16 studies using the Mixed Methods Appraisal Tool, showcasing diverse bioactive compounds for diabetes.
  • The findings highlight a need for well-designed human trials, as current evidence is limited to animal studies and shows design heterogeneity.

Cite This Study

Firdaus et al. (2025) studied this question.

synapsesocial.com/papers/68ec384042a190b2c35199cahttps://doi.org/10.7324/japs.2026.234652
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  4. 4The Effect of Sargassum fusiforme and Fucus vesiculosus on Continuous Glucose Levels in Overweight Patients with Type 2 Diabetes Mellitus: A Feasibility Randomized, Double-Blind, Placebo-Controlled Trial2024 · 5 citations
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