A Comprehensive Review of Treatment Outcomes in Lichen Planus Pigmentosus

Lichen Planus Pigmentosus (LPP) has been a topic of debate and extensive research both with respect to its existence and its treatment. Many treatment options have evolved from topical to systemic each one emerging as an effective treatment in one or the other patient. This may be due to its varied presentations and association with other systemic conditions. Through this study we aimed to review the current literature available to draw a conclusion on treatment available and its outcome in cases of LPP. The objective of this study was to evaluate the efficacy of both topical and systemic treatment for LPP and list down the side effects associated with different treatments used in these studies. A thorough literature search was done through Pubmed, Medknow, Scopus, clinical trial registry etc using key words “lichen planus pigmentosus” “treatment of lichen planus pigmentosus”, lasers in LPP, chemical peels in LPP. Efficay and safety all treatments used in LPP were evaluated and accordingly results and conclusions were drawn. The conclusion drawn at the end of study was that both topical mometasone and topical tacrolimus proved to be effective in early LPP but oral agents as dapsone, isotretinoin, tranexamic acid, hydroxychloroquine give better results without many side effects. Further, LASERs and chemical peels can also be tried in non- responding cases of post LPP hyperpigmentation.