Composition‐Engineered Quantum Dots for Visible Light‐Driven Copper‐Catalyzed Click Chemistry

Quantum dots (QDs) are emerging as high‐performance photocatalysts, surpassing conventional systems through their superior light‐harvesting efficiency, tunable electronic properties, and robust charge carrier dynamics. Here, compositionally tuned Zn x Cd 1‐x S QDs ( x = 0.0–1.0) are systematically optimized for visible light‐driven copper‐catalyzed azide–alkyne cycloaddition (CuAAC), a pivotal reaction in organic synthesis. Zn 0 . 1 Cd 0 . 9 S QDs ( x = 0.1) exhibit an exceptional 99.5% triazole yield within 4 h, significantly outperforming conventional CdS QDs (6 h). Their finely tuned 2.72 eV bandgap, precisely aligned with 456 nm blue light, enhances charge separation and accelerates catalytic efficiency. These QDs demonstrate broad substrate scope, excellent functional group tolerance, high recyclability (81% efficiency over 10 cycles), and scalability (93% gram‐scale yield), maintaining structural integrity as confirmed by morphological and spectroscopic analyses. This work establishes compositionally engineered QDs as advanced, durable photocatalysts, providing a transformative approach to sustainable CuAAC chemistry and broader nanomaterial‐driven applications.