Histogenesis of Liver in Human Fetuses

The liver is the largest gland of our body, having both exocrine and endocrine function. In the third week of IUI liver arises as ventral outgrowth from the foregut endoderm. Development of liver is an ongoing process that begins after fertilization and continues into postnatal liver. It is an essential organ having extensive power of regeneration. The present study of histogenesis of liver in human fetuses is to unravel the sequence of events in the different weeks of gestation. Method: 30 human fetuses ranging between 16–40 weeks of gestation were studied after staining with H&E stains under a light microscope. The fetal liver bet Result: ween 16–40 weeks of intrauterine gestation shows hepatocytes and haemopoietic cells. Haemopoietic cells decrease in amount towards term. Hepatic lobule becomes apparent after 20 weeks, and Kuffer cells appear after 26 weeks. We saw the portal triad at 16 weeks onwards till term. The present study gave Conclusion: emphasis on detail histogenesis of human fetal liver in the prenatal period ranging from 16–40 weeks of gestation, which is more or less similar with previous studies.