This study observes the influence of treatable traits on exacerbations in bronchiectasis, suggesting improvements in patient care.
Exacerbations of bronchiectasis are heterogeneous events characterized by worsening symptoms and increased infection. These episodes impair patients' quality of life and increase mortality. They also serve as crucial indicators when monitoring disease progression and assessing therapeutic interventions. The Treatable traits' strategy is a model of care that targets multiple modifiable characteristics to deliver precision medicine and improve clinical prognosis. This study focuses on treatable traits including respiratory infections, airway inflammation, respiratory symptoms, comorbidities, underlying aetiologies, and behavioural or lifestyle factors. It examines their association with bronchiectasis exacerbations, with the aim of enabling the clinical implementation of this framework for reducing exacerbation frequency.
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Xia et al. (2025) studied this question.
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