Case report identifies pulmonary involvement in intravascular large B-cell lymphoma, suggesting improved diagnostic strategies.
Intravascular large B-cell lymphoma (IVLBCL) represents a rare subtype of extranodal lymphoma characterized by the proliferation of B-cells within the lumen of blood vessels. Pulmonary involvement occurs in approximately 60% of cases. Diagnosis of IVLBCL can be challenging as the clinical manifestations are usually nonspecific. We report a case of IVLBCL presenting with fever and dyspnea. CT scan revealed bilateral diffuse pulmonary ground-glass opacities with gravity-dependent distribution. The diagnosis was established through transbronchial lung biopsy. This case report aimed to heighten clinical awareness and sharpen diagnostic skills regarding pulmonary involvement in IVLBCL.
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Shi et al. (2025) studied this question.
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