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October 15, 2025BMC Infectious DiseasesOpen Access

Clinical characteristics of Mycoplasma pneumoniae compared to Streptococcus pneumoniae in hospitalized adults with community-acquired pneumonia- a prospective study

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Authors

KHKarin HansenLWLisa WasserstromJAJonas Ahl

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Overview

Prospective analysis compared clinical features in 158 hospitalized adults with CAP, suggesting expanded testing for mycoplasma pneumoniae.

Key Points

  • Younger patients with mycoplasma pneumoniae had a median age of 39 years compared to 70 years for those with streptococcus pneumoniae.
  • Mycoplasma pneumoniae accounted for only 6% of community-acquired pneumonia cases overall, but 33% in patients under 50 years.
  • Clinical symptoms and chest imaging could not reliably distinguish mycoplasma from streptococcus pneumoniae infections.
  • Inflammatory marker levels like CRP were significantly lower in mycoplasma pneumoniae CAP, despite still being elevated.

Cite This Study

Hansen et al. (2025) studied this question.

synapsesocial.com/papers/68efbd16d61273c8652d8166https://doi.org/10.1186/s12879-025-11811-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical features of severe Mycoplasma pneumoniae pneumonia in adults admitted to an intensive care unit2007 · 122 citations
  2. 2Detection of Mycoplasma Pneumoniae Using Targeted Next-Generation Sequencing: A Comparative Analysis of Clinical Characteristics in Pure Infections and Co-Infections2024
  3. 3Clinical and laboratory features of pediatric Mycoplasma pneumoniae Pneumonia with viral versus bacterial co-infection2026
  4. 4Age-related clinical differences in children with Mycoplasma pneumoniae infection.2026
  5. 5P-681. Evaluation of Clinical Characteristics and Antimicrobial Stewardship Interventions in Mycoplasma pneumoniae Infections at a Community Teaching Hospital2026