Power spectral analysis of EEG of brain electrical activity in female patients with epilepsy

Background: Changes in low frequency waves and altered psychological status were associated with epilepsy. Epilepsy can cause anxiety and depression and many other complications and anti-seizure medication can make the patients lethargic, tired and drowsy.Objective: To assess and quantify cortical brain waves in female patients with epilepsy by power spectral analysis of signals of quantitative electroencephalogram(QEEG). Methods: This study was carried out on 20 female patients with epilepsy aged 20-40 years and 20 healthy female volunteer of similar age were control. EEG was recorded from 22 scalp electrodes in different region all over the head by an EEG data acquisition device, EEG Traveler Brain Tech 32+ CMEEG-01, India in all participants. Power spectral analysis of EEG data was done with Brain Tech 40+ Standard version 4.47a analysis software by calculating relative band power of delta, theta, alpha and beta brainwaves to assess cortical electrical activity. Data were expressed as mean ± SD. For statistical analysis, Independent-Samples t test was used. The P value ≤ 0.05 was considered as statistical significance. Results: Mean values of relative power of delta and theta were significantly higher and values of alpha and beta were significantly lower in all cortical areas of epilepsy patients compared to control. Conclusion: It may be concluded that higher low frequency brain wave and lower high frequency brain wave were associated with epilepsy. J Bangladesh Soc Physiol 2025;20(1): 1-9