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Fundamentals of ctDNA Biomarkers in Tumor Precision Medicine

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ctDNA is a critical biomarker that enhances the landscape of precision medicine, providing insights from diagnosis to treatment monitoring.
Recent advancements in digital PCR and next-generation sequencing have improved ctDNA detection sensitivity and quantification in diverse clinical scenarios.
Clinical applications of ctDNA include early cancer detection and monitoring tumor progression, which are essential for personalized treatment strategies.
Future research focuses on developing new technologies and integrating AI to overcome challenges associated with ctDNA sampling and analysis.

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Analytical innovations improve ctDNA detection and precision medicine approaches in various cancers, suggesting transformative applications.

Ruan et al. (2025) studied this question.

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Analytical innovations improve ctDNA detection and precision medicine approaches in various cancers, suggesting transformative applications.