Novel hydrogel-based Bio-Block® platform preserves adipose-derived MSC traits and secretome, suggesting enhanced regenerative potential.
Background/Aims Mesenchymal stem/stromal cells (MSCs) are widely investigated for regenerative therapies, yet current expansion methods often compromise their stem-like properties, limiting large-scale clinical translation. We aimed to evaluate whether a novel hydrogel-based Bio-Block® platform preserved intrinsic adipose-derived MSC (ASCs) phenotype and secretome compared with conventional systems.
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Hodge et al. (2025) studied this question.
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